Many owners assume that any replacement part carrying the right part number will perform just like the original equipment. This assumption often leads to premature engine failure because subtle differences in internal machining make a massive difference under high heat.
Selecting the Best Aftermarket Lifters for 5.7 Hemi requires looking past the part number and focusing on durability and compatibility. I put together these insights to help you choose hardware that keeps your engine running smoothly for years to come.
Key Takeaways
- Decide if you truly need to retain the Multi-Displacement System or if a permanent delete kit is better for your driving style.
- Check that your chosen lifters match the specific production year and model of your engine to avoid oil pressure issues.
- Prioritize high-quality metallurgy to handle the heavy valve spring pressure common in modern performance setups.
- Ensure your kit includes the necessary hardware like trays or plugs if you choose to move away from factory systems.
- Consider purchasing a full camshaft and lifter kit if your existing components show any signs of metal shavings or wear.
| Industry Standard Precision | ![]() |
COMP Cams Hydraulic Roller Lifter Set | High manufacturing standards | Smooth operation | Proven reliability | View on Amazon | Read Review |
| Reliable Factory Replacement | ![]() |
Koomaha MDS Hydraulic Lifter Set | Direct fit replacement | Retains fuel efficiency | Consistent hydraulic pressure | View on Amazon | Read Review |
| Daily Driver Essential | ![]() |
Standard MDS Replacement Lifter Set | Precise fitment | Restores smooth idle | Cost-effective maintenance solution | View on Amazon | Read Review |
| Conversion Project Staple | ![]() |
Non-MDS Performance Lifter Set | Removes MDS failure points | Durable construction | Excellent for cam swaps | View on Amazon | Read Review |
| Budget Restoration Choice | ![]() |
MDS V8 Replacement Lifter Set | Fits factory trays | Standard oil pressure response | Reliable daily performance | View on Amazon | Read Review |
| Complete Conversion Package | ![]() |
Non-MDS Lifter and Plug Kit | Includes necessary oil plugs | Simplifies engine architecture | High durability components | View on Amazon | Read Review |
| Workshop Value Option | ![]() |
16-Piece MDS Hydraulic Lifter Set | Complete 16-piece set | Matches factory specifications | Quiet valve operation | View on Amazon | Read Review |
| Comprehensive Rebuild Solution | ![]() |
MDS Camshaft and Lifter Kit | Includes essential gaskets | Complete system renewal | Perfectly matched components | View on Amazon | Read Review |
| Affordable Maintenance Replacement | ![]() |
GELUOXI MDS Hydraulic Lifter Set | Budget-friendly price | Direct fitment | Restores engine rhythm | View on Amazon | Read Review |
| Performance Conversion Bundle | ![]() |
Non-MDS Camshaft and Lifter Kit | Includes conversion gaskets | Durable lifter design | Simplifies valvetrain maintenance | View on Amazon | Read Review |
More Details on Our Top Picks
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COMP Cams Hydraulic Roller Lifter Set
If you want to move away from factory components, this set is the gold standard for many Hemi owners. These lifters offer consistent performance across the entire RPM range, which makes them a reliable choice for street-driven vehicles.
You should choose these if you value proven engineering over budget options. The only downside is that they require a break-in period to ensure the roller wheels seat correctly against your camshaft lobes.
- Brand Name:COMP Cams
- Lifter Type:Hydraulic Roller
- Engine Compatibility:5.7L Hemi
- Part Numbers:856-16
- Quantity Included:16
- Additional Feature:Engineered for performance
- Additional Feature:Precision machined components
- Additional Feature:Designed for hydraulic profiles
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Koomaha MDS Hydraulic Lifter Set
Replacing your Multi-Displacement System (MDS) components is a major job, and these units provide a solid path to restoration. They match the original equipment specifications, ensuring that your vehicle retains its fuel-saving cylinder deactivation features.
These are best for drivers looking to return their engine to stock performance levels. Just be aware that they are designed specifically for MDS engines and cannot be used in a Non-MDS conversion project.
- Brand Name:Koomaha
- Lifter Type:MDS Hydraulic
- Engine Compatibility:5.7L Hemi
- Part Numbers:53021726AD, 53021726AE
- Quantity Included:16
- Additional Feature:Matches OEM dimensions
- Additional Feature:Compatible with active fuel management
- Additional Feature:Standard flow rate
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Standard MDS Replacement Lifter Set
Sometimes you just need a functional replacement that gets your Dodge or Chrysler back on the road without complications. These lifters maintain the factory geometry required to keep your MDS system functioning as the manufacturer intended.
These are an ideal choice for a standard maintenance overhaul on a high-mileage engine. One limitation is the lack of performance hardening, so they are not suited for high-lift camshaft upgrades.
- Lifter Type:MDS Hydraulic
- Engine Compatibility:5.7L Hemi
- Part Numbers:53021726AE, 53021726AD
- Quantity Included:16
- Additional Feature:OEM replacement design
- Additional Feature:Maintains MDS function
- Additional Feature:Standard hydraulic internal springs
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Non-MDS Performance Lifter Set
Switching to a Non-MDS setup is a popular way to improve engine longevity and responsiveness. These lifters are built to handle the constant firing of all eight cylinders, effectively removing the complexity of the factory deactivation system.
These work well if you are pairing them with a performance camshaft or simply eliminating potential failure points. Keep in mind that you must update your ECU tuning when installing these, as the computer will expect the MDS system to be present.
- Lifter Type:Non-MDS Hydraulic
- Engine Compatibility:5.7L, 6.1L, 6.4L Hemi
- Part Numbers:5038784AD, 53021720AA
- Quantity Included:16
- Additional Feature:Fixed valve actuation
- Additional Feature:Solid architecture
- Additional Feature:Eliminates deactivation hardware
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MDS V8 Replacement Lifter Set
When you are staring at a torn-down engine, having a reliable set of replacement lifters is the most important part of the rebuild. These units function just like the factory originals, providing the necessary oil flow for the MDS system to engage and disengage.
They are perfect for a weekend garage project where you need to get the engine sealed up quickly. Note that they do not include the lifter trays, so you should make sure yours are in good shape before starting.
- Lifter Type:MDS Hydraulic
- Engine Compatibility:5.7L Hemi
- Part Numbers:53021726AE, 53021726AD
- Quantity Included:16
- Additional Feature:OEM-style hydraulic internals
- Additional Feature:Easy drop-in installation
- Additional Feature:Standard oil port placement
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Non-MDS Lifter and Plug Kit
Converting a Hemi is like trying to change the rules of a game halfway through, so having the right parts is critical. This kit includes the essential plugs needed to block off the oil passages that would otherwise feed the old MDS system.
This is the best kit for enthusiasts who want to get rid of the MDS system permanently. Because this is a specialized conversion kit, you should have a solid understanding of Hemi engine internals before you start the tear-down.
- Lifter Type:Non-MDS Hydraulic
- Engine Compatibility:5.7L, 6.1L, 6.4L Hemi
- Part Numbers:5038784AD, 53021720AB
- Quantity Included:16 lifters, 4 plugs
- Additional Feature:Includes oil valley plugs
- Additional Feature:Conversion-ready hardware
- Additional Feature:Simplified mechanical design
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16-Piece MDS Hydraulic Lifter Set
If you are performing a full cylinder head service, you need a complete set of 16 lifters to ensure uniform operation. This set provides the correct tension to keep your valvetrain quiet and responsive during normal daily commutes.
These are a straightforward choice for those who want to stick with the original manufacturer design. One minor drawback is that the shipping packaging can sometimes be flimsy, so inspect each lifter for surface defects before the installation.
- Lifter Type:MDS Hydraulic
- Engine Compatibility:5.7L Hemi
- Part Numbers:53021726AD, 53021726AE
- Quantity Included:16
- Additional Feature:Consistent hydraulic response
- Additional Feature:Standard metallurgy
- Additional Feature:Fits stock camshafts
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MDS Camshaft and Lifter Kit
Sometimes it is easier to buy a bundled kit than to hunt down individual gaskets and components. By replacing the lifters along with the head gaskets and camshaft, you ensure that all parts are seating together for the first time.
This is the smartest move if your engine has suffered a major valvetrain failure. You will need to account for the extra time required to swap the entire top end, but the results are worth the effort.
- Brand Name:Unbranded/Generic
- Lifter Type:MDS Hydraulic
- Engine Compatibility:5.7L Hemi
- Part Numbers:HS26423PT, 53021726AD
- Quantity Included:16 lifters plus gaskets
- Additional Feature:Bundled head gaskets
- Additional Feature:Camshaft included
- Additional Feature:Total top-end refresh
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GELUOXI MDS Hydraulic Lifter Set
If your Hemi has developed that dreaded ticking sound, it is often the lifters crying out for a replacement. These units provide a cost-conscious alternative to buying from the dealership while maintaining the same operational design.
These are great for a budget-friendly repair on an older truck or SUV. Just remember that they are intended for standard driving conditions, so avoid using them in high-performance or high-revving racing applications.
- Brand Name:GELUOXI
- Lifter Type:MDS Hydraulic
- Engine Compatibility:5.7L Hemi
- Part Numbers:53021726AD, 53021726AE
- Quantity Included:16
- Additional Feature:OEM-style construction
- Additional Feature:Standard hydraulic travel
- Additional Feature:Simple installation process
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Non-MDS Camshaft and Lifter Kit
Moving your Hemi to a Non-MDS format is often a decision made to increase reliability during high-performance use. This kit provides everything you need to finish the task, including the necessary gaskets and the lifters themselves.
This is a solid option for anyone looking to simplify their engine and build a more durable platform. Since this is a conversion kit, ensure that your engine computer is tuned to handle the removal of the MDS solenoids.
- Lifter Type:Non-MDS Hydraulic
- Engine Compatibility:5.7L Hemi
- Part Numbers:HS26423PT, 53021720AD
- Quantity Included:16 lifters plus gaskets
- Additional Feature:Conversion-specific hardware
- Additional Feature:Head gasket set included
- Additional Feature:Optimized for stable firing
Frequently Asked Questions
Why do 5.7 Hemi lifters fail so often?
The primary culprit is often the MDS system or simple heat soak that degrades the internal check valves. When the plastic lifter trays wear out, the lifter rotates, causing the roller to grind against the cam lobe instead of rolling smoothly.
Should I delete the MDS when replacing lifters?
Many enthusiasts choose to delete the MDS because it removes the complex hardware that often causes lifter noise and failure. By switching to a non-MDS camshaft and lifter set, you increase engine reliability and simplify your valvetrain architecture.
How do I know if my lifters are failing?
Listen for a distinct ticking or tapping sound that increases in frequency as engine RPM rises. If you notice a misfire code or a rough idle, pull the valve covers to check for excessive lash in the rocker arms.
Do I need to replace the camshaft when I change lifters?
If your current lifters have already started to score the cam lobes, you must replace the camshaft. Reusing a damaged cam with new lifters will destroy your new components in a matter of minutes.
Is it necessary to soak new lifters in oil before installation?
Yes, you should soak them in clean engine oil for several hours before putting them into the block. This helps remove trapped air and ensures the hydraulic plunger is primed for the initial startup, which prevents scuffing.

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